China's COVID-19 inactivated vaccines available by 2020 end

One in seven volunteers for Sputnik V report side effects

18 Sep 2020 One in seven volunteers for Sputnik V report side effects Written by Shubham Sharma Science

"India is amongst most severely impacted countries from COVID-19 and we believe our human adenovirus dual vector platform will provide a safe and scientifically validated option to India in the battle against COVID 19", RDIF CEO Kirill Dmitriev said.

It is the first coronavirus vaccine to be cleared for human use globally even though the final trials began earlier this month. Under the agreement, Russia's sovereign wealth fund will supply 100 million doses of Russia's COVID-19 vaccine to Indian drug maker. "These vaccines are in different stages of pre-clinical and clinical development of which three candidates are in advanced stage of Phase I/II/III trials and four are in advanced pre-clinical development stage", Vardhan said. "Nationally, almost 30 vaccine candidates are under development, by both industry and academia".

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Despite the alarms, Russian Federation has been moving ahead with the production and distribution of the vaccine (for those at high-risk) while carrying out the late-stage trials at the same time.

Sputnik V was registered by the Russian Ministry of Health in August 2020. It is under post-registration clinical trials involving 40,000 volunteers. The Indian Express reported on September 15 that the firm has been in talks to ascertain whether it can successfully incorporate the Russian vaccine's technology, and scale up production at its facility. However, scientists and healthcare experts cautioned against the use of Sputnik V which has not passed full safety and efficacy checks.

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Dr. Thacker, who is also an executive director of the International Pediatric Association, said there may be ways to fast-track the trials, but transparency was crucial. The first results of these trials are expected to be published in October-November 2020, the RDIF said in its statement.

As reported, Murashko said that the symptoms after being injected with the Russian COVID-19 vaccine "level off" by the next day and the complications are "described in the instructions and are predictable". "The platform of human adenoviral vectors, which is the core of the Russian vaccine, has been tested in more than 250 clinical studies over decades, and it has been found safe with no potential negative long-term consequences".

When will COVID-19 vaccines be generally available in the U.S.?
The trial will be initiated in the second half of October after the vaccine is manufactured by SII. Largescale clinical trials on Sputnik V involving 40,000 volunteers are now ongoing.


China has stated that it will make its COVID-19 vaccine a global public good when available, contributing to vaccine accessibility and affordability in developing countries. But doctors say that the severity of the virus may be decreasing.

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