Oxford Covid-19 vaccine trials resume after patient fell ill

Kazakhstan reaches an agreement with Russia on the supply of vaccine against coronavirus

Oxford and AstraZeneca: the reprise of COVID-19 vaccine trial

After receiving information from the British health authorities, Anvisa authorized the reactivation of the trials also in Brazil, concluding "that the benefit/risk ratio remains favorable".

Temporary halts are common in vaccine trials, but the pause on the front-runner for the coronavirus raised eyebrows earlier this month as at least 176 ongoing research efforts as medical leaders in countries across the world race to deliver a vaccine to get a hold on the coronavirus pandemic.

While Russia has already begun inoculating volunteers as part of a third phase of trials of the country's "Sputnik V", Denis Logunov, the deputy research director at the Gamaleya Center who is leading the group developing Russia's first coronavirus vaccine, shares his take on what to expect from the COVID-19 vaccine.

Russian Federation was criticized in the West for allegedly rushing the development of Sputnik V, and for rolling out the vaccine before concluding a third stage of clinical trials.

In a statement, the university said that in large trials "it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety".

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At the same time, the suspension of trials clearly showed the fallacy of the approach, when entire countries exclusively rely on novel and untested platforms when choosing a vaccine.

Participants in the clinical trials will not be informed of which vaccine they are receiving.

AstraZeneca also says it can not disclose further medical information because it is the study sponsor, but added in its statement, "All trial investigators and participants will be updated with the relevant information, and this will be disclosed on global clinical registries, according to the clinical trial and regulatory standards".

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"It is planned that a batch of vaccines for delivery to Kazakhstan will be produced by one of the worldwide partners of RDIF", the Russian fund said in a statement.

AstraZeneca says trials of vaccine resuming
But, Moscow's decision to grant approval for its vaccine before finishing clinical trials has raised concerns among some experts. There are at least 35 vaccines in clinical trials around the world, nine of which are in Phase 3, the final stage of testing.


Health Minister Greg Hunt says there is genuine hope a vaccine being developed in the United Kingdom will be available in the first half of next year.

"Russia did not even publish its trials until a few days ago when it did in The Lancet, a peer-reviewed journal".

Although initial studies didn't reveal serious side effects from the vaccine, rare complications of any vaccine, if there are any, may not turn up until it has been administered to thousands, or tens or thousands of people.

However, the drugmaker suspended late-stage trials this week after a participant in Britain suffered neurological symptoms.

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