AstraZeneca says trials of vaccine resuming

AstraZeneca's Oxford vaccine trial to resume, the university says

AstraZeneca says trials of vaccine resuming

But, Moscow's decision to grant approval for its vaccine before finishing clinical trials has raised concerns among some experts.

Oxford University confirmed the resumption and said: "In large trials such as this, it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety". This was followed by the first phase of trials on human subjects to test for safety, vaccine effectiveness, and the standard dose needed to produce antibodies at an appropriate level. There are at least 35 vaccines in clinical trials around the world, nine of which are in Phase 3, the final stage of testing.

On Sept. 6, AstraZeneca says, all studies around the world of this particular candidate vaccine were paused after one volunteer in the United Kingdom developed symptoms consistent with transverse myelitis, an inflammation of the spinal cord that can cause paralysis. The goal of the large studies is to see if the vaccine is capable of preventing COVID-19, and is safe. It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 (COVID-19 virus spike protein).

Egypt's Health and Population Ministry announced that starting Sunday it would open volunteer registration for the third phase of the coronavirus vaccine clinical trials, done in cooperation with the Chinese government and the UAE health care company G42.

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"The first batches of the vaccine for testing the supply chain have already been shipped, we are now checking the delivery system so that the staff gets to know it".

"The postponement of the clinical trial also puts into question the request of some of the pharma companies for full indemnification from any risks from their vaccines by purchasing countries". The companies promised to wait until they had adequate data showing any potential vaccine worked safely.

About 18,000 people have received the vaccine, according to The University of Oxford, which helped develop the vaccine with AstraZeneca.

Pauses in drug trials are commonplace and the temporary hold led to a sharp fall in AstraZeneca's share price following the announcement Tuesday.

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No details of the nature of the side effect have been given.

"I think one would have to say that we're on the edge of losing control", Mark Walport, the British government's former chief scientific adviser, told BBC radio.

The World Health Organization (WHO) stated almost 180 vaccine candidates are being tested around the world.

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