BioNTech and Pfizer's COVID-19 vaccine shows potential in trial

Will the Pfizer vaccine solve the coronavirus crisis?			 0					By		LLB Editor		 		at				10:49

Will the Pfizer vaccine solve the coronavirus crisis? 0 By LLB Editor at 10:49

A potential vaccine by major phamacuetical company Pfizer and German partner BioNTech has shown promising results, and is expected to advance to the next trial phase by the end of July. The small study triggered stronger immune responses in recipients. Dr. David Agus joined "CBS This Morning" with the latest on the global vaccine effort.

"Our first vaccine candidate is eliciting antibody levels to neutralize the virus that is equivalent to or better than what you see in people who have had COVID-19". At the 10 µg or 30 µg dose levels, the scientists said adverse reactions, including low grade fever, were more common after the second dose than the first dose.

He said larger trials were being prepared to show whether this translates into protection against a real infection.

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While there hasn't been a COVID-19 vaccine approved for commercial use yet, BioNTech and Pfizer's drug is one of the 17 potential vaccines that are being tested in humans at the moment.

Early-stage human trials of vaccines are created to measure certain antibodies and other immune markers in the blood as an indicator of the body's readiness to fight an infection that then requires further validation. It was first detected in China late a year ago. This vaccine, called BNT162b1, is the most advanced of the four.

London shares closed higher on Thursday as signs of progress in developing a COVID-19 vaccine bolstered hopes of a post-pandemic economic recovery, while Primark-owner Associated British Foods gained after issuing an upbeat trading update.

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Early studies of the vaccine BNT162b1, one of four candidates to fight the virus, which is now being developed by Pfizer, all patients that were vaccinated at 28 days were identified neutralizing antibodies. BioNTech and Pfizer continue to ramp up manufacturing capacity, with plans to produce up to 100 million doses by the end of 2020 and over 1.2 billion by the end of 2021.

Biotech investors Thomas and Andreas Struengmann, who sold their generic drugs business Hexal to Novartis in 2005, are major shareholders of BioNTech.

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