Eastern Time from Kennedy's Launch Complex 39A.
SpaceX has become a household name in recent years with the company launching, and landing, dozens of rockets. A crucial decision point will come at T-minus-45 minutes, when the go-ahead is due to be given for arming the Dragon's launch escape system and fueling up the Falcon 9 rocket with highly refined kerosene and liquid oxygen. This can then be reused for future flights to help reduce costs. SpaceX has just test-fired the Falcon 9's first-stage engines as part of the final series of tests needed before launch.
Many of these missions have been to deliver supplies to the International Space Station (ISS) or to loft satellites into orbit around the Earth.
If SpaceX doesn't launch Wednesday, its next attempt would be Saturday.
The Demo-2 mission will be the first manned mission to launch from the U.S. since the retirement of the Space Shuttle in 2011.
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The Demo-2 mission will launch atop a Falcon 9 rocket and carry the astronauts toward the International Space Station at around 17,000 miles per hour (27,360 km/h).
One America's Lilia Fifield spoke to NASA administrator Jim Bridenstine to discuss this historic mission.
The launch is scheduled for 4:33 p.m. ET on Wednesday, May 27.
Built entirely by SpaceX with funds awarded by NASA, the company's Crew Dragon spacecraft and Falcon 9 rocket will effectively singlehandedly return the United States' ability to launch its own astronauts. Among those that will be in attendance include President Donald Trump and Vice President Mike Pence.
Get set for a new American Space Age.
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The first manual test will occur on the evening of the launch.
The weather around the Kennedy Space Center in Florida may have other ideas, however.
The only threat to the launch, at this stage, is the 60% chance of unfavourable weather conditions according to Cape Canaveral forecasters, and agency officials have noted that this figure is trending upwards in a press conference earlier today.
Not only does the weather need to be tranquil around the launchpad, but also downrange over the Atlantic Ocean in the event that the crew needs to abort and safely splash down in the ocean.
During the mission, Behnken and Hurley will test critical components of the Crew Dragon, such as its artificial environment, displays, control system, manoeuvring thrusters, and so on.
Both the astronauts have extensive experience in space and been involved in NASA's Space Shuttle flights.
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Bettman said the hub cities have yet to be determined, but Toronto, Edmonton and Vancouver are on the league's short list. All personnel must be 6 feet apart while inside and outside of the facility.
"We've looked at this six ways to Sunday, so it's not that I think this will fail", Aviation Week's Irene Klotz quoted Musk as saying.