But he hit back at Washington, accusing it of seeking to repeatedly "attack and smear" China.
Wang Yi also warned the USA against trying to change China, defended Beijing's handling of the pandemic and made a case for more control of Hong Kong in a news conference that lasted over an hour and a half.
Relations between Washington and Beijing recently deteriorated as the USA accused China of misinformation about the coronavirus crisis.
China's President Xi Jinping has insisted such an investigation will not be allowed until the pandemic boils over.
On maritime disputes in the South China Sea, Wang blamed rising tensions on the presence of foreign military aircraft and warships - rather than Chinese vessels. China, he said, was a victim like everyone else, hinting that his country would fight what he termed "fabrications".
Bollywood actor Kiran Kumar tests positive for COVID-19
Veteran Bollywood actor Kiran Kumar has been diagnosed with coronavirus, according to reports published by the Indian media. I'm alone and reliving my boarding school days, putting my own bed and washing my own clothes (laughs)".
State Councillor Wang, speaking at his annual news conference on the sidelines of China's parliament, expressed his deep sympathies to the US for the pandemic, where the death toll is expected to surpass 100,000 in the coming days, the highest by any country.
China's foreign minister on Sunday argued that political forces in the USA are pushing the two powers into a new Cold War when they should be cooperating against the coronavirus.
"China has no intention to change the U.S., nor to replace the U.S. It is also wishful thinking for the U.S.to change China", Wang said Sunday during his annual news briefing on the sidelines of National People's Congress meetings in Beijing. "Some politicians completely disregard basic facts and have fabricated too many lies targeting China, and plotted too many conspiracies", China's Foreign Affairs Minister concluded.
But he called for co-operation between Washington and Beijing in tackling the outbreak.
What's the bigger picture here?
Two more positive COVID-19 cases in EPL
Since the players returned to limited group training on Tuesday, eight positive tests for the virus have been confirmed. The Cherries confirmed the player has contracted the virus after the latest round of tests for top flight clubs.
U.S. lawmakers have advanced several pieces of legislation targeting China in recent weeks with bipartisan support amid mounting calls for lawmakers to punish Beijing for its alleged failure to disclose information early on about the spread of Covid-19.
Longstanding friction between the two powers over trade, human rights and other issues have been pushed to new heights since the COVID-19 outbreak.
Noting that China remains committed to jointly developing ties marked by coordination, cooperation and stability with the United States, Wang said China will defend its sovereignty and territorial integrity, its legitimate right to development, and its dignity and place in the world which the Chinese people have worked so hard to earn.
He also defended the World Health Organization and its head Tedros Adhanom Ghebreyesus, who has been the target of recent United States criticism.
As per the new legislation, many freedoms that the island nation has been reportedly abolished, and gives more control to China.
L'Amérique du Sud, "nouvel épicentre" du coronavirus - Édition digitale de Bruxelles
Le gouvernement français, qui a déploré cette décision, a menacé Londres d'une " mesure de réciprocité ". Les bars ont ainsi rouvert au Texas, sous réserve de se limiter à un quart de leur capacité d'accueil.