Lancet study: HCQ may harm patients

They estimated that the excess risk attributable to the use of the drug regimen rather than other factors such as co-morbidities ranged from 34% to 45%. Others are vaccine candidates who will teach the immune system to create its own antibodies that kill COVID-19. "However, we now know from our study that the chance that these medications improve outcomes in COVID-19 is quite low". "Each of these drug regimens was associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias when used for treatment of COVID-19". However, science is responding with evidence to the contrary, and a massive study of hydroxychloroquine reveals that the drug does more harm than good. And yes, that "damage, quot; can include death".

"A Trump enemy statement", he said of one study.

Dr Marcos Espinal, director of the Pan American Health Organization - part of the World Health Organization - has stressed that no clinical trials have recommended the use of hydroxychloroquine for coronavirus.

They then played a clip of the president's "reckless" promotion of the drug, during which he calls hydroxychloroquine "a gift from heaven" but admits he is not a doctor.

The New York Times has reported there may be more to Trump's determined promotion of the drug as certain pharmaceutical companies will profit if it is accepted as a COVID-19 treatment.

No new cases of COVID-19 today
One person has died in Wood County of complications surrounding the coronavirus (COVID-19), health officials confirmed today. The Health Ministry said the NZ COVID Tracer app has recorded 324,000 registrations since it was released on Tuesday night.


The drugs are fairly safe for patients being treated for malaria, but Covid-19 is a very different disease.

Several more recent studies have not shown the drug to be an effective COVID-19 treatment.

Trump's criticism of the studies also comes as his allies have been eager to counter messaging from public health experts who say Trump is putting lives at risk by pushing states to quickly reopen in an election year.

They also determined that about one in 11 patients who hadn't been treated with either chloroquine or hydroxychloroquine died in hospital, compared to death rates of about one in six for those who took the drugs. The study could be the final nail in the coffin of this drug when it comes to coronavirus cures.

The researchers acknowledged observational studies can not account for unmeasured confounding factors but added, "our findings suggest not only an absence of therapeutic benefit but also potential harm with the use of hydroxychloroquine or chloroquine drug regimens (with or without a macrolide) in hospitalized patients with COVID-19". The patients had a mean age of 54.

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It looked at patients who were administered the drugs either alone or in combination with a type of antibiotic known as a macrolide within 48 hours of their COVID-19 diagnosis. One in five who was given chloroquine with an antibiotic and one in four given hydroxychloroquine with an antibiotic, perished. Add an antibiotic and the risk of arrhythmia jumps to 311%.

Mehra said the use of hydroxychloroquine for COVID-19 is unwise. "I wish I had this information from the beginning", he said, "since there has potentially been harm to the patients". The work was posted online for researchers and has not been reviewed by other scientists.

"If there was ever hope for this drug, this is the death of it", said Topol.

At the end of the study period around nine per cent of those in the control group had died.

Results from some of the first large, randomized studies of hydroxychloroquine are expected soon, including a study being conducted by the French government and one at the University of Minnesota.

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Eighty-four people died from COVID-19 in the past 24 hours, down from 109 the previous day - and the lowest total since March 24. Andrew Cuomo is allowing New Yorkers to legally gather in small groups.


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