The CDC did not immediately comment on the new case, which would be the 13th in the United States after a patient was confirmed in Wisconsin last Wednesday.
The adult patient was among USA nationals evacuated from Wuhan, the epicenter of the disease, who were under mandatory quarantine for 14 days at Marine Corps Air Station Miramar, near San Diego, local television station 10News reported.
"The confirmed positive patient was returned to UC San Diego Health for observation and isolation until cleared by the CDC for release".
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"CDC is conducting a thorough contact investigation of the person who has tested positive to determine contacts and to assess if those contacts had high-risk exposures", the CDC said in a statement, without giving further details.
Some 540 United States nationals have been evacuated from Wuhan and flown to the Miramar base where they are subject to the CDC's first public health quarantine in 50 years.
The US has imposed mandatory quarantines and travel restrictions with China to slow the spread of coronavirus within the country.
China's national health commission said on Tuesday the death toll had reached 1,016, up 108 from the day before, including 103 in Hubei province and the first time more than 100 deaths had been reported in one day.
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The individual was among four patients taken to the UC San Diego Medical Center for further evaluation last week.
An evacuee from China has tested positive for the coronavirus and has been isolated at a San Diego hospital, The Associated Press has learned.
Another person at Miramar was also hospitalized on Monday afternoon and was being tested for the coronavirus.
"Both patients are doing well and have minimal symptoms,"the hospital said".
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With most US-China flights suspended, only a handful of US nationals arriving on commercial flights have been quarantined under rules imposed on Feb 2 to curb the virus' spread, according to a Reuters survey. NY reported four people and IL a "tiny" number, the survey found.