Argentina fell behind when Edinson Cavani, who scored in Uruguay's 2-1 win over Hungary on Friday, notched his 50th global goal in the 34th minute.
Argentina showed loads of promise going forward in hope for the opener, but equally so the Uruguayans threw the gauntlet with Suarez having a shot blocked after 20 minutes.
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Winston passed for 313 yards and two touchdowns in the loss, but turnovers were his downfall as has often been the case. Evans did snare the longest pass of that game, a 41-yarder that set up Godwin's touchdown.
After quiet start to the second half, the equaliser duly arrived when Aguero headed home from a close-range following a pin-point delivery from partner-in-crime Messi on 63 minutes.
A turnaround didn't materialise though as Suarez hauled his side back five minutes later with an astounding free-kick from the edge of the area.
Messi's free kick from the left was nodded home by Sergio Aguero to put a more realistic sheen on the scoreline for the Argentines, who had been the more positive side throughout.
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There was a long-awaited reunion outside the Penn State locker room, and KJ Hamler was wound up and at the center of it all. Heading into its game on Saturday against Rutgers, the Buckeyes had not been challenged for four quarters by any opponent.
Messi missed a penalty and scored on the rebound in a 1-0 win over Brazil three days ago, but he made no mistake from the spot on this occasion and clinched the draw in the 92nd minute.
Uruguay's lead was quickly restored, though, when Suarez's whipped free-kick from 25 yards proved too powerful for Andrada to keep out. Up stepped Messi who would score.
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Watchmen showrunner Damon Lindelof also hopped on board, coyly pleading the fifth on whether he's even seen the Snyder cut . Snyder quote-tweeted Gadot's tweet and wrote , "The ancient Amazonian can't be wrong".