Second half goals from Nicolas Pépé, Jonathan Bamba, Gabriel dos Santos Magalhaes and Jose Fonte gave Lille a resounding victory.
Qatar Sports Investment have invested more than one billion euros ($1.13 billion) on players since they took control in 2011.
Pepe was denied by Areola before Dani Alves made a crucial intervention as Loic Remy went for goal, but it would still get worse for the champions as ex-Southampton defender Fonte headed in Pepe's corner for a fifth. Mbappe saw his another goal ruled offside in the 13th minute.
However, the Spanish full-back was shown a straight red card shortly before the break when he brought down Pepe as the striker was rushing towards goal.
Two minutes later, Mbappe expertly set up Bernat's volleyed equalizer and, just two minutes after that, Mbappe ran through and finished superbly - only for the flag to come up once again.
Soaking storm in store for Easter and Passover weekend
And long weekend planning means looking at the weather pattern, and seeing if it's patio (or Easter egg hunting) appropriate yet. Tonight any showers that develop will diminish shortly after sunrise and with decreasing clouds lows will drop in the low 40s.
"We can't lack personality like that, and concede three, four, five goals".
"Bernat played on the left, then the middle, it's not normal".
"Moussa Diaby has played only twice and (Thilo) Kehrer is sick - ordinarily they should not be with us, but here we are".
"We are missing too many players, and nobody is speaking about it".
United Kingdom retail sales surge as consumers ignore Brexit and keep shopping
The UK consumer price index rate was 1.9% in March, unchanged from February, according to the Office for National Statistics . He continued: "We suspect house prices will rise only 1% over the year and would not be at all surprised if they stagnate".
"There are 18 points left to play for - so I will let my players enjoy this for 48 hours, even if they have training on Monday", said a delighted Christophe Galtier. We lost Lassana Diarra and Adrien Rabiot, while Neymar, Edinson Cavani, Angel Di Maria, Marquinhos and Thiago Silva have missed weeks at a time.
"Nobody is saying anything about this, though, as we keep winning".
"With 10 players it became complicated, we played with sick players who should not have played".
Beyoncé drops new 'Homecoming live' album, documentary
Featured on the end credits to the documentary, the 37-year-old has covered Frankie Beverly and Maze's 1981 track Before I Let Go .