In spring, domestic airline companies conduct over 50 flights everyday to Lukla, known as Tenzing Hillary airport.
The injured, who included a police personnel, have been airlifted to Kathmandu for treatment.
Reports say the plane skidded off the runway to the right and hit the helicopter that had just landed from Kathmandu - cutting it in two.
The paper said that "the deceased include Summit Air's co-pilot Sunil Dhungana and Assistant Sub-Inspector of Police Ram Bahadur Khadka, who was stationed in Lukla for airport security".
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Three people have died after a small plane crashed into a helicopter that was parked up during takeoff at an airstrip close to Mount Everest. They are undergoing treatment at Grande International Hospital.
'We are not sure about the cause of the accident'.
The Kathmandu Post reported that Airport authorities probing into the matter believe the co-pilot had significantly few flying hours amounting to less than a year and a half experience before taking on the World's Most Dangerous Airport.
Four of the passengers and a flight attendant on board the plane were safe, civil administrator Narendra Kumar Rama said.
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The airport - called the gateway to Mount Everest - is one of the world's most risky because of the short runway and the mountainous surroundings. Only helicopters and small winged aircraft are allowed in this airspace.
It is also popular as Lukla is the place where most people begin to climb the Mount Everest Base Camp.
Earlier, in February Seven people, including the country's tourism minister when a helicopter crashed in the hilly east.
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