Gum infection may be linked to Alzheimers disease: Study | newkerala.com #93787

Research: It may be possible to restore memory function in Alzheimer's, preclinical study finds

Gum disease–causing bacteria could spur Alzheimer's

They also discovered bacterial enzymes called gingipains that destroy brain cells were present, too.

Mice are nocturnal animals, tau levels in fluids surrounding brain cells were found to be twice as high at night when they were more awake and active than during the day when they dozed more frequently; disturbing rest during the day caused daytime tau levels to double.

'The upcoming clinical trial will be a crucial test to see if this can be a potential treatment for Alzheimer's'.

The pharmaceutical company, which is focused on developing therapeutics to alter the course of Alzheimer's disease, funded the research.

The Washington University School of Medicine in St. Louis also suggests that proper sleep can help maintain good brain health.

"There's a relationship [between gum disease and Alzheimer's], but the relationship does not necessarily mean cause and effect".

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A new study suggests that it may be more hard to detect Alzheimer's disease (AD) in Hispanic patients.

"Information from our study can help guide how we assess living Hispanic patients who may have Alzheimer's, to more accurately detect the disease in its early stages". But a spinal tap is the only way to get the fluid, and many people are reluctant to have one.

Gingivitis causes the gums to become red, swollen, bleed easily - and, according to a new study, it might also cause Alzheimer's when it goes untreated for decades. After all, signs of P. gingivalis were found in up to half the brain tissue samples of people without the disease. The study is ongoing.

"Our recent paper is about the blood brain barrier breakdown", Zlokovic said. The result suggests the bacterium may play a role in driving the development of the disease, researchers reported yesterday (January 23) in Science Advances. Her team previously found that P. gingivalis actively invades the brains of mice with gum infections.

Now there is no single test to diagnose Alzheimer's, and this NfL test is not yet approved by the FDA to diagnose or predict brain damage.

Jucker likened his team's work to the cancer field. And when mice that had been genetically engineered to have Alzheimer's were infected with gum disease, their dementia symptoms worsen.

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Sunday, Feb. 24, the Glenn Biggs Institute will host a panel discussion at the Tobin Center titled "Protecting your Brain from Alzheimer's Disease: A Panel Discussion on the Role of Sleep, Stress, Diet and Exercise". A vaccine for gum disease would be welcome - but if it also stops Alzheimer's the impact could be enormous.

Gum disease affects an estimated 45% of the United Kingdom population, according to the British Dental Association (BDA).

This is not the first blood test developed in hope of diagnosing the disease early.

DNA tests on three brains with Alzheimer's disease and six healthy brains also had the gene associated with P. gingivalis in their tissue.

"Forgetting something that's recently learned, not doing things we do on a daily basis such as hygiene or taking medications and living in different passages of time are all examples of symptoms of Alheimer's and Dementia", Ligeza said".

Although the gum disease and Alzheimer's link has been mixed in various studies, Lynch explains that the link they revealed is much more statistically significant than in previous research. Researchers say this "meaningful" link allows them to predict the disease's progression.

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Furthermore, Yan outlined the importance of an epigenetic process being applied to all brain disorders because this type of approach controls not just one, but many genes and these types of disorders are often polygenetic diseases.

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