Speaking outside Number 10, the Prime Minister said: "I firmly believe that the draft withdrawal agreement was the best that could be negotiated and it was for the Cabinet to decide whether to move on in the talks".
She vowed to get the deal signed off in Brussels and put it to a vote of MPs.
Brexit Secretary Dominc Raab MP, Work and Pensions Secretary Esther McVey MP, Fareham MP Suella Braverman and Northern Ireland minister Shailesh Vara are all amongst the MPs who quit cabinet positions today (November 15).
A vote will be triggered if 48 Tory MPs write letters to Sir Graham. It is understood 48 letters have not yet been received.
Mr Rees-Mogg told reporters that United Kingdom negotiating team had "given way on all the key points" adding: "The deal risks Brexit because it is not a proper Brexit".
Macron et Merkel dévoilent une plaque pour commémorer l'armistice de 1918
Retrouvez toutes les photos de la commémoration du 11 novembre dans notre diaporama. Des propos qui ont visiblement fait plaisir au président américain .
He sent a message to the British people: "As much as I am sad to see you leave, I will do everything to make this farewell the least painful possible, both for you and for us".
She acknowledged the agreement had entailed "difficult and sometimes uncomfortable decisions".
"The prime minister said she "didn't quite hear the question" and then denied she had said Brexit might not happen?" "They are looking to the Conservative Party to deliver".
"It is my job as prime minister to explain the decisions that the government has taken and I stand ready to do that beginning tomorrow with a statement in parliament".
Media captionBBC's Laura Kuenssberg asks the PM if she "in office, but not really in power?"
Anderson remporte le match inaugural — Nitto ATP Finals
Dans la soirée, Roger Federer s'est montré presque aussi cruel avec Dominic Thiem , s'imposant 6-2, 6-3 en 1h07. Les spectateurs de l'O2 Arena n'en ont pas vraiment eu pour leur argent ce mardi.
Asked Thursday evening whether she would fight a confidence vote, May swiped at her critics, saying her draft deal was in the national interest, not her own political interest.
"Now, when we're making progress and close to a deal he's complaining about that".
"I can not in good conscience support the terms proposed for our deal with the EU", Raab said in a tweet.
Numerous MPs were contacted for comment but, although it is widely expected the vast majority will back the prime minister, most were unwilling to fully back Mrs May at this stage.
Macron fait un déplacement rapide (320 km/h) au Maroc
La SNCF assure quant à elle l'assistance à maîtrise d'ouvrage auprès de l'Office National des Chemins de Fer marocains ( ONCF ). Le président Emmanuel Macron se rend jeudi au Maroc pour une visite de quelques heures.