Eric Dier will captain a side that is likely to include goalkeeper Jack Butland, defenders James Tarkowski, Kyle Walker and Danny Rose, midfielders Ruben Loftus-Cheek and Fabian Delph, plus striker Danny Welbeck.
So, take a look at the slideshow above to see which players we feel were fortunate to wear the three lions as one of England's elite.
England will be back in action in October with a UEFA Nations League double trip against Spain and Croatia.
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Liverpool's backline has been a subject of headlines and this is the area which has sparked numerous questions from so many years. Liverpool are set to hand new contracts to Trent Alexander-Arnold and Joe Gomez, according to The Sun .
When asked to stack up England's most talented players against the likes of Spain's Andres Iniesta, Xavi and David Silva, Southgate said: "The only one in my lifetime is Paul Gascoigne and I'm not sure he was developed, I think he was a outcome of a unique talent".
"Over the next few weeks, what we are hoping is that we have given them some minutes, they go back to their club better prepared for when they get their opportunity and it gives them a better chance of staying in the team". The 20-year-old is set to score this season for the club and was sent off last time out against Burnley.
The game was also a reminder of just how unbearable the England band are.
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He admitted that he was thrilled at the prospect of trying out a new challenge but since Bayern was one of the biggest clubs in the world, it was hard for him to walk away.
Southgate insisted after being outplayed for the majority of a 2-1 defeat by Spain in his side's inaugural Nations League encounter on Saturday that England must persist with his intention to improve on playing out from the back under pressure. "It is even more complicated". "He's a huge admirer of him, but he's got his job to do", Southgate maintained.
It was Rashford's fifth goal for England in 27 matches. "It was important then that we solved a couple of the problems they were facing and kept things calm", Southgate said. "He would have been a bit disappointed about the amount of time he had at the World Cup but it was important to get him in the penalty box and remembering the areas where he needs to be scoring goals".
Since establishing himself in Spurs' starting line-up at the start of the 2014-15 season, Kane has barely missed a game for club or country, clocking up 232 appearances for his club as well as for England's senior team and the U21s.
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And the Lions could be without their best defensive player, pass-rusher Ziggy Ansah, who exited the game with a shoulder injury. "I think it was very evident that there were a lot of opportunities we missed out there", Shanahan said.