Brighton stunned a lacklustre Manchester United with three first-half goals to secure a famous victory at the Amex Stadium.
Pogba thumped a speculative effort well over with United struggling to make any headway against the well-organised home side - but after 34 minutes they found a way back, Shaw's bouncing, deflected ball into the area glanced home by Lukaku.
Paul Pogba's penalty in second-half stoppage time was too little, too late for disjointed United.
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"They've been weak, United have been weak", Souness said on Sky Sports.
Victor Lindelof surpassed Bailly's tackle record, as he failed to make any successful tackles during the game, and to add insult to injury failed to make any blocks at all during the 90 minutes, with United's central defence partnership failing to make any interceptions.
Goal! Lukaku pulls one back for United with a header!
This was an improvement on their display in last season's 1-0 home win over the same opponents and will give the manager hope of a top-half finish this term.
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Antonio Valencia has spent nine seasons at Old Trafford and was named as the first choice captain for the majority of last season.
Mourinho was unhappy with the Amazon Prime documentary revealing comments from inside the City dressing room during their title-winning season, which he felt were derogatory towards himself and United.
The Italian full-back is facing increased competition for a starting place after Mourinho signed Diogo Dalot in a £17m deal from Portuguese giants FC Porto this summer.
But the damage had already been done as Brighton sat comfortably on their lead until virtually the last kick of the match.
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Both signed by Mourinho for a combined fee of £60 million, they have started the season as first choice, but it would be no surprise if they were both sat in the stands when Tottenham turn up at Old Trafford on August 27. Fred is likely to be sat at the base of a three-man midfield and will be charged with breaking up the play and kick-starting United attacks on the break.