"Syria's air defense shot down two Israeli missiles, both were destroyed in the area of the Kiswa in the province of Damascus", - said the press service.
He refuses to answer if Putin has asked the Israeli Air Force to refrain from violating Syrian airspace, as the Russian president had during a recent phone call between the leaders following an alleged Israeli airstrike on Iranian targets in the war-torn country.
Asked about those statements, an Israeli military spokeswoman said: "We do not respond to such foreign reports".
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"Iran is now seeking to implant very risky weapons in Syria to be used against Israel for the specific objective of our destruction".
Israel, which nearly never confirms or denies airstrikes in Syria, did not comment on Tuesday's attack.
Occasional clashes have erupted between Israel and the Syrian regime and its Hezbollah ally in the Golan Heights, occupied by Israel since 1967. The Syrian Observatory said the casualty number from Tuesday's strike is likely to go up because of a large number of people who were wounded and a number of people who are missing.
Asked if Israel retaliated for the salvo, he said: "We have retaliated but I have no further details about this". Israel has not confirmed or denied involvement.
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McCain announced last summer that he is battling an aggressive form of brain cancer - the same type that killed his friend, Sen. Orrin Hatch , called McCain's decision "ridiculous", and said he would choose differently because Trump is "a very good man".
The strikes, "probably Israeli", targeted a military airport in Aleppo in the country's north and Brigade 47 in Hama, where Iranian forces are stationed, the Observatory said.
His trip Wednesday came as Syrian state-run media said Israel struck a military outpost near the capital, Damascus, the previous night.
Tensions between Iran and Israel rose dramatically in the lead-up to Mr Trump's decision on the nuclear deal.
Abdel Rahman said the strike had killed at least nine pro-regime fighters, "including members of the Iranian Revolutionary Guard and other pro-Iranian Shiite militiamen", but it was not possible to independently confirm any toll.
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