Sunset Valley police says it started assisting the Federal Bureau of Investigation around 6:30 a.m.by providing perimeter security as it investigates.
His comments during a White House meeting with Saudi Arabia's Crown Prince Mohammed bin Salman came after a fifth package exploded on a conveyor belt in an FedEx package sorting facility near San Antonio.
This follows a fourth explosion in Austin Sunday that injured two people. About 6:45 a.m., Draylen Mason, 17, was killed from a package explosion, while his mother was seriously injured. "But we're not saying that that's the cause as well", the chief added.
No injuries have been reported in the explosion at FedEx, ATF spokeswoman Nicole Strong said.
An exploding package on March 2 killed a 39 year-old man.
An employee was hurt after a "single package exploded", FedEx spokesman Jim McCluskey told CNN.
A FedEx Office on Brodie Lane is closed.
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"We are clearly dealing with what we expect to be a serial bomber at this point, based on the similarities between what is now the fourth device", he told reporters. "So that's why I want to reiterate the importance that if you see something that's out of place, do not handle it, do not move it, do not touch it. Call us", Manley said. The city's fire department said a hazmat team was there to help with the investigation.
According to Sunset Valley police, the package was from a South Austin FedEx location on Brodie Lane to be sent to an address in Austin.
Austin Mayor Steve Adler on Tuesday sought to reassure citizens.
Who is responsible for the Austin bombings?
"As each tip comes in, it gets assigned to either a team of Federal Bureau of Investigation agents, ATF agents or Austin Police detectives to do follow-up work on", he said.
"We're going to be here for a little while", Smith said. Police are still investigating the second most recent attack that occurred Sunday evening, injuring two young men.
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Investigators believe the Austin bombings are related, Manley said, "because of some of the specific components of these devices".
Here's what we know - and don't know - about the series of Austin bombings that have only escalated fear among a city of almost 1 million people.
"There has not been an effort from the attacker to get publicity, and quite a few attackers are interested in what they see as glory and attention", Pape said in a telephone interview.
"If this bomber is being motivated, in part, by the sense of power and control that he has holding the city of Austin in a state of fear, and depending how addictive that feeling is", she said, "that can be a strong contributor to his doing it again and not waiting a long period of time".
But police believe all the bombings are connected, although the latest one appeared to be activated by a trip wire while the others were concealed in packages left on doorsteps.
The other four parcel bombs blew up in the Austin area. "I think everybody can now say, 'Oh, that's like my neighbourhood, '" he said.
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Twitter user Delaine Gordon B added: "This is just one more example of how Hollyweird empowers women!" Others pointed out that the arguments against the artwork could be seen as hypocritical.