A former housing minister, Sisulu takes over a post previously occupied by Maite Nkoana-Mashabane, who was named minister of rural development and land reform.
The ANC Youth League says it is disappointed with President Cyril Ramaphosa's new Cabinet, because he has left young people behind.
After being unceremoniously booted out from former president Jacob Zuma's Cabinet in a midnight cabinet reshuffle in March previous year, former finance minister Pravin Gordhan makes a triumphant return to take charge of the ministry of Public Enterprises.
Nhlanhla Nene's previous term as finance minister was from May 2014 until December 2015, when he was sacked by then-President Jacob Zuma, a move that saw an angry reaction in financial circles. The SACP congratulates the Ministers and Deputy Ministers the President appointed‚ and thanks former Ministers and Deputy Ministers for their efforts - where these were in the interests of the people rather than private motives.
Four days later, Mr Gordhan was appointed to the role to calm the markets.
Davis Cup to be transformed into a 1-week World Cup
The ITF on Friday announced its plan to transform the Davis Cup competition with backing from investment group Kosmos. Remarkably, Barcelona and Spain superstar Gerard Pique is the founder and president of the investment group Kosmos .
The date of Zuma's first court appearance is also yet to be decided. He was handed the key public enterprises department, which oversees around 300 state-owned firms, including loss-making South African Airways and cash-strapped power utility Eskom. Gordhan, who trained as a pharmacist, headed the national tax agency before serving as finance minister from 2009 to 2014. "We warned that Ramaphosa is only interested in careerism, and has no demonstrable history of integrity and fighting corruption". Ten ministers were dropped altogether from cabinet, a majority of them key Zuma allies.
"I can say now that this matter needs to be attended to immediately, with the greatest of urgency", Ramaphosa told traditional leaders on the land issue at a meeting in parliament after he made changes to his cabinet on Monday night.
President Ramaphosa said the leadership of the ANC was still coming up with proposals for the reconfiguration of a new Cabinet.
The Democratic Alliance opposition party has also reacted, saying the new changes show that the country's problems lie with the ANC.
Former President Zuma's tenure had been marred by allegations of corruption and factionalism within the party.
Pienaar: Why I Chose To Retire
He then moved to Everton on-loan for the 2007-08 season before signing a three-year permanent deal with the Merseysiders. This was the first of many accolades the technically gifted midfielder would revel in during his career.
Deputy President: David MabuzaCyril Ramaphosa embraces David Mabuza during the 54th national conference of the ANC in Johannesburg on December 18, 2017.
Ramaphosa has been praised for appointing his former rival in the ANC Presidential race, Nkosazana Dlamini-Zuma, the former African Union boss and ex-wife to former President Jacob Zuma. Zuma's chief henchman‚ David Mahlobo‚ also got the chop‚ as did the man who replaced him as state security minister last year‚ Bongani Bongo.
The rand firmed against the dollar in volatile trade, ahead of the announcement, and was steady after Ramaphosa spelt out the changes.
Ramaphosa announced that finance minister Malusi Gigaba and his deputy Sfiso Buthelezi were out.
Mining, which is vital to South Africa's economy, received a new minister - Gwede Mantashe - who was eagerly welcomed by the industry.
Bayer to win EU approval for $62.5 billion Monsanto deal
The prescription-drug division, still Bayer's biggest unit, was a bright spot. -With assistance from Aoife White. Addressing the FDA's concerns will drive Ebitda down by about 300 million euros, Bayer said.
Widely known by his initials DD, Mabuza has been accused of helping to rig state tenders and having his opponents in Mpumalanga silenced - accusations he has denied.